Q; 21 years old male who just returned from Indian subcontinent is admitted to ICU with severe dehydration and hypotension. Patient is diagnosed with cholera. One of the main pathology in cholera is that the intestines cannot absorb water and electrolytes, and results in large secreting diarrhea?
A) True
B) False
Answer: B
Despite cholera pathogen present, the intestines could still absorb water and electrolytes. This holds true despite large secreting diarrhea. This seems trivial but this is the basis of management in cholera with fluid resuscitation, hydration and repletion of electrolytes.
#infectious-diseases
References:
Muanprasat C, Chatsudthipong V. Cholera: pathophysiology and emerging therapeutic targets. Future Med Chem. 2013 May;5(7):781-98. doi: 10.4155/fmc.13.42. PMID: 23651092.
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