Q: In the initial phase of Negative Pressure Wound Therapy (NPWT) - Wound Vac - the perfusion is increased?
It is beyond the scope of this website to describe in detail the working of Wound-Vac. The negative pressure system of wound-vac generates a pressure gradient between the wound and suction canister. This negative pressure transports the fluid from wound bed and interstitial space and reduces wound edema. It also causes cell/tissue modulation. The pressure applied in wound-vac is 5-10 mmHg. Also, the foam in wound-vac system contracts and draws the edges of the wound together.
Wound-Vac has also many indirect effects of wound healing. The major indirect effects are
- Alterations in blood flow
- Diminished inflammatory response
- Altered bacterial burden
- Changes in wound biochemistry