Q: Eosinophilia is one of the essential features of "drug fever." (select one)
It has been estimated that about one-third of patients in the hospital develop drug fever. No absolute reason is known but it is assumed that this is due to subclinical allergic or allergic-type (idiosyncratic) reaction. Also, it can be due to an effect on thermoregulation system.
Although eosinophilia is common in drug fever it occurs only in one-fourth of the patients.
Reference:Mackowiak PA, LeMaistre CF. Drug fever: a critical appraisal of conventional concepts. An analysis of 51 episodes in two Dallas hospitals and 97 episodes reported in the English literature. Ann Intern Med 1987; 106:728.