Sunday, May 30, 2021

simethicone add in the bowel preparation

 Q: 58 years old male is admitted to ICU with lower gastrointestinal bleed (LGIB). Consulting service requests to add simethicone to the bowel preparation. What is the advantage of adding simethicone to bowel preparation? 

Answer: Visualization during colonoscopy can be restricted due to the high gas bubbles burden. Simethicone is used during the procedure to reduce gas bubbles. Simethicone use in the midst of the procedure carries an inherent risk of contamination. This persists despite proper procedures followed for disinfection and reprocessing methods. This objective can be achieved by adding simethicone to the bowel preparation before the procedure./span>



1. Barakat MT, Huang RJ, Banerjee S. Simethicone is retained in endoscopes despite reprocessing: impact of its use on working channel fluid retention and adenosine triphosphate bioluminescence values (with video). Gastrointest Endosc 2019; 89:115. 

2. Moraveji S, Casner N, Bashashati M, et al. The role of oral simethicone on the adenoma detection rate and other quality indicators of screening colonoscopy: a randomized, controlled, observer-blinded clinical trial. Gastrointest Endosc 2019; 90:141.

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