Q: Gallstone ileus is due to? (select one)
A) mechanical bowel obstruction
B) non-mechanical bowel obstruction
Answer: A
Gallstones can easily pass through the intestine except at few places such as ileum, the narrowest part of the intestine. It can also occur at the jejunum and stomach. In patients with prior pathology causing strictures such as inflammatory bowel disease, abdominal surgeries, or diverticulitis, it carries a high risk.
It can also occur after endoscopic sphincterotomy where a large enough stone can cause obstruction. It frequently occurs concurrently with the Mirizzi syndrome (common hepatic duct obstruction due to extrinsic compression from impacted stone in cystic duct). The narrowing of the common hepatic duct can cause cholecystenteric fistula, creating a pathologic exit route for stones. Mirizzi syndrome was first described by Mirizzi more than 70 years ago.
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