Case: 62 years old female recently diagnosed with open-angle glaucoma, otherwise healthy, is admitted to ICU with severe airway obstruction requiring a non-invasive ventilation mask. Which drug is probably the culprit?
Answer: Topical Beta-blocker (BB)
This question aims to establish that topical BB can lead to severe airway obstruction, even in patients with no established history of airway disease. Topical BB should be considered a systemic treatment and prescribed cautiously in patients with underlying lung and heart disease.
#pulmonary
#opthalmology
References:
1. Kirwan JF, Nightingale JA, Bunce C, Wormald R. Beta blockers for glaucoma and excess risk of airways obstruction: population based cohort study. BMJ 2002; 325:1396.
2. Kirwan JF, Nightingale JA, Bunce C, Wormald R. Do selective topical beta antagonists for glaucoma have respiratory side effects? Br J Ophthalmol 2004; 88:196.
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