Saturday, June 8, 2024

Visual functions and adverse ocular effects in patients with amiodarone

Q: What could be the ocular side effects of Amiodarone?


Answer: Most side effects are due to Amiodarone intracytoplasmic lamellar deposits in the cornea, lens, retina, and optic nerve.
  • Colored rings around lights.
  • Corneal epithelial opacities resembling a cat's whiskers
  • Lens opacity
  • Retinopathy (rare)
  • Optic neuropathy

#pharmacology



References:

1. Mäntyjärvi M, Tuppurainen K, Ikäheimo K. Ocular side effects of amiodarone. Surv Ophthalmol. 1998 Jan-Feb;42(4):360-6. doi: 10.1016/s0039-6257(97)00118-5. PMID: 9493278.

2. Ikäheimo K, Kettunen R, Mäntyjärvi M. Visual functions and adverse ocular effects in patients with amiodarone medication. Acta Ophthalmol Scand. 2002 Feb;80(1):59-63. doi: 10.1034/j.1600-0420.2002.800112.x. PMID: 11906306.

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