Friday, October 7, 2011

Q; Is Digoxin a diuretic?

A: Yes it has direct diuretic property! Digoxin increases diuresis by at least 4 mechanisms
  • Direct vasodilation
  • Increased CO improves renal hemodynamics
  • Inhibition of tubular reabsorption of sodium, of renal Na+ -K+-ATPase, and of concentrating and diluting ability
  • Increased secretion of atrial natriuretic peptide

1. Rahimtoola SH, Tak T. The use of digitalis in heart failure. Curr Probl Cardiol. 1996; 21: 781–756

No comments:

Post a Comment