Q: prothrombin complex concentrate, human  is contra-indicated in which one condition frequently encounter in ICU?

Answer: Heparin Induced Thrombocytopenia (HIT)

prothrombin complex concentrate (popularly known as PCC or with its trade name K-Centra) does not contain any preservatives but the excipients are human antithrombin III, heparin, human albumin, sodium chloride, and sodium citrate. 

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