Q: Why sotalol is preferred over other Beta-Blockers for prevention of V. Tach. and V.fib.?

Answer: Due to its Dual action.

Sotalol is a non-selective β-blocker that also exhibits Class III antiarrhythmic properties by its inhibition of potassium channels. Because of this dual action, Sotalol prolongs both the PR interval and the QT interval. Sotalol is often preferred over other β-blockers as prevention and treatment for both ventricular fibrillation and ventricular tachycardia.