A note on inhaled Milrinone

(instead of systemic Milrinone)

The major advantage of inhaled milrinone is its pulmonary selectivity, thereby avoiding systemic side effects and ventilation-perfusion mismatch. Inhaled milrinone is an effective pulmonary vasodilator and appears to be an alternative promising approach in addressing the problem of right-ventricular decompensation following cardiopulmonary bypass.

Reference:

Wang H, Gong M, Zhou B, Dai A. - Comparison of inhaled and intravenous milrinone in patients with pulmonary hypertension undergoing mitral valve surgery. -  Adv Ther. 2009 Apr;26(4):462-8