Q: Which of the following antihypertensive may be use in treatment of myelodysplastic syndrome (MDS)?

A) Lopressor

B) Clonidine

C) Lisinopril

D) Hydralazine

E) Methyldopa 

Answer:  D 

Hydralazine has also been used successfully as a treatment for myelodysplastic syndrome in its capacity as a DNA methyltransferase inhibitor along with magnesium valproate.

Reference:

Candelaria, M; Herrera, A; Labardini, J; González-Fierro, A; Trejo-Becerril, C; Taja-Chayeb, L; Pérez-Cárdenas, E; Cruz-Hernández, E; Arias-Bofill, D; Vidal, S; Cervera, E; Dueñas-Gonzalez, A (5 October 2010). "Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial". Annals of Hematology 90 (4): 379–387