Q: All of the following decrease the effectiveness of Adenosine except?\

A) caffeine,

B) theophylline

C) chocolate

D) carbamazepine

Answer:  D 

In ICU,  Adenosine is a common drug used for termination of Supra Ventricular Tachycardia (SVT).  It is important to know the interactions of various drugs with Adenosine as it may require either higher or lower than standard "push" of Adenosine.

People with habit of drinking lot of coffee(caffeine) or tea(theophylline) or consuming large amount of chocolate(theobromine) may require higher than usual dose of Adenosine. In contrast, carbamazepine or dipyridamole may increase the effect of adenosine.