Q: Which of the following is found to resolve the acute episode of sweet syndrome (acute febrile neutrophilic dermatosis)?

A) Methotrexate 
B) IV antibiotics
C) Potassium iodide
D) Aspirin
E) Hemodialysis


Answer: C

Steroids are well known to help in Sweet Syndrome but potassium iodide is found to be equally effective, resolving fever within 2 days and cutaneous lesions within 3-4 days.Recommended dose is 300 mg of potassium iodide three times daily. Modus operandi of Potassium Iodide in Sweet Syndrome is thought to be immune suppression. Patient should be watched for pulmonary edema.