Friday, February 17, 2017

Q: When all measures fail in acute exacerbation of idiopathic Pulmonary Fibrosis (AE-IPF), lung transplant should be pursue aggressively as a last resort of salvage therapy..

A) True
B) False

Answer: B

Lung transplantation in IPF has sown good outcome only if its done as an elective process. It should not pursue as a salvage therapy in AE-IPF. It carries a very high mortality rate. Lately, some centers are using extracorporeal membrane oxygenation (ECMO) as a bridge to transplant (BTT) in AE-IPF, but data is still very thin. Ideally, all patients with IPF should undergo transplant evaluation while they are clinically at their baseline.


 Yusen RD, Edwards LB, Kucheryavaya AY, et al. The Registry of the International Society for Heart and Lung Transplantation: Thirty-second Official Adult Lung and Heart-Lung Transplantation Report--2015; Focus Theme: Early Graft Failure. J Heart Lung Transplant 2015; 34:1264.

No comments:

Post a Comment