Q: Why  wound deformation is desired in Negative pressure wound therapy (NPWT) (Wound-vac)?


Answer: The negative pressure  in NPWT deforms the edges of the wound together and firmly apposes any skin grafts/flaps. Tissue deformation stimulates tissue remodeling at the cellular level.



References:

Urschel JD, Scott PG, Williams HT. The effect of mechanical stress on soft and hard tissue repair; a review. Br J Plast Surg 1988; 41:182.