Q: What is Delta toxin?
Answer: Delta toxin is a hemolytic peptide secreted by Staphylococcus aureus. This toxin is also known as Delta-lysin or septicolysin as it is lytic to cells by solubilization of their membranes. Also, it has direct and indirect effects on the activity of neutrophils and monocytes which confers to its proinflammatory property.
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References:
1. Dhople, V. M. and Nagaraj, R. Prot. Eng. 8, 315 (1995), Dhople, V. M. and Nagaraj, R. Peptides 26, 217 (2005). Send to J Infect Dis. 1997 Dec;176(6):1531-7.
2. Schmitz FJ, Veldkamp KE, Van Kessel KP, Verhoef J, Van Strijp JA. Delta-toxin from Staphylococcus aureus as a costimulator of human neutrophil oxidative burst. J Infect Dis. 1997 Dec;176(6):1531-7.
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