Q: Treatment of native and prosthetic valve candida endocarditis requires both (combine) antifungal medical therapy and surgical valve replacement? (select one)
It is true that there is some evidence to support only antifungal medical therapy for the treatment of native and prosthetic valve candida endocarditis but the latest guidelines from the Infectious Diseases Society of America (IDSA) and the American Heart Association (AHA) recommends a combined medical and surgical treatment for the treatment of native as well as prosthetic valve candida endocarditis.
1. Pappas PG, Kauffman CA, Andes DR, et al. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis 2016; 62:e1.
2. Baddour LM, Wilson WR, Bayer AS, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association. Circulation 2015; 132:1435.