Monday, June 17, 2019


Q: Intravenous lipid emulsions (ILEs) are getting popular as a treatment of choice in the overdose of many drugs. Name few side-effects of its administration?

Answer: ILEs are fastly getting acceptance as one of the treatments in drugs overdose. But it comes with its own perils. Some of the possible side-effects of its administration include:

  • acute kidney injury
  • cardiac arrest
  • ventilation-perfusion mismatch
  • acute lung injury
  • venous thromboembolism
  • hypersensitivity
  • fat embolism
  • pancreatitis
  • extracorporeal circulation machine (ECMO) circuit obstruction
  • increased susceptibility to infection
  • priapism 


1. Bryan D. Hayes et al. Systematic review of clinical adverse events reported after acute intravenous lipid emulsion administration. Clinical Toxicology Volume 54, 2016 - Issue 5

2. Priapism in patients treated with total parenteral nutrition. Ekström B, Olsson AM. Br J Urol. 1987 Feb; 59(2):170-1.

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