Q: Name a few conditions which may give false positive digoxin level despite no digoxin is ingested?
Answer: It is interesting that few clinical conditions may give positive digoxin level even if there is no digoxin ingested. It may mislead the clinician. This is particularly important in patients with subarachnoid hemorrhage (SAH), liver insufficiency, and renal insufficiency. This phenomenon is also reported in pregnant women, newborns, and in patients with acromegaly.
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Reference:
Dasgupta A. Endogenous and exogenous digoxin-like immunoreactive substances: impact on therapeutic drug monitoring of digoxin. Am J Clin Pathol 2002; 118:132.
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