Q: Salicylate poisoning causes? (select one)
A) Hyperpnea and tachypnea
B) Hypopnea and tachypnea
Answer: A
The objective of the above question is to highlight that in salicylate (aspirin) poisoning, one of the physical signs is not only the increased rate but also the increased depth of the respiration, called hyperpnea. This becomes more vital to identify as this is one of the earliest sign of salicylate poisoning. Later it may culminate into hypoventilation and respiratory failure due to muscles fatigue. This is a central effect due to the activation of the respiratory center of the medulla.
#toxicology
#pulmonary
References:
1. Hill JB. Salicylate intoxication. N Engl J Med 1973; 288:1110.
2. Greenberg MI, Hendrickson RG, Hofman M. Deleterious effects of endotracheal intubation in salicylate poisoning. Ann Emerg Med 2003; 41:583.
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