Q: Prior use of inhaled glucocorticoids in COPD or asthma patients ___________ the chance of parapneumonic effusions? (select one)
Surprisingly, prior use of inhaled glucocorticoids in patients with underlying asthma or chronic obstructive pulmonary disease (COPD) lessens the risk of parapneumonic effusions. Experts are not sure, is this a real phenomenon due to an altered inflammatory response from inhaled glucocorticoids, or these patients have a low threshold to seek medical care early.
1. Sellares J, López-Giraldo A, Lucena C, et al. Influence of previous use of inhaled corticoids on the development of pleural effusion in community-acquired pneumonia. Am J Respir Crit Care Med 2013; 187:1241.