Q: Which of the following anti-psychotics is more prone to cause extrapyramidal symptoms (EPS)? (select one)
A) Haloperidol
B) Quetiapine
C) Clozapine
D) Iloperidone
Answer: A
Antipsychotics are frequently used in ICU. Extrapyramidal symptoms (EPS) are common after their use. Extrapyramidal symptoms usually consist of akathisia, parkinsonism, and dystonias. Few well-known antipsychotics to cause EPS are haloperidol, fluphenazine, thiothixene, and trifluoperazine. One of the objectives of this question is to emphasize the side-effect of haloperidol which is still in high use by inpatient clinicians.
Quetiapine, clozapine, and iloperidone are less intend to cause EPS.
#neurology
#pharmacology
References:
JOHN MUENCH, MD, MPH. ANN M. HAMER, PharmD, BCPP. Adverse Effects of Antipsychotic Medications Am Fam Physician. 2010 Mar 1;81(5):617-622.
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