Q: Elevated procalcitonin can be used reliably to add antibiotics in hospitalized COVID-19 patients?
In advance COVID-19 patients, despite lack of any other evidence for infections, procalcitonin levels are found to be elevated. It is up to clinician discretion in such cases to add or hold back on antibiotics. The prudent thing would be to draw blood cultures, sputum culture and perform urinanalysis (UA) and decide in conjugation with other clinical evidence. Infectious Disease (ID) consult may be helpful too.
A low procalcitonin level may be more helpful in deciding against the addition of antibiotics.
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