acute uremic encephalopathy

 Q: What is the usual lag time of recovery in acute uremic encephalopathy? 

Answer: About 24-48 hours after dialysis

Acute uremic encephalopathy is one of the indications of emergent dialysis, though the lag time for recovery is about 24-48 hours. Symptoms range from just fatigue to seizures and coma. Some patients may have a unique finding consisting of myoclonic jerks, twitching, or fasciculations known as uremic twitch-convulsive syndrome.

#nephrology

#neurology

References:

1. Bolton CF, Young GB. Uremic encephalopathy. In: Neurological Complications of Renal Disease, Bolton CF, Young GB (Eds), Butterworths, 1990. p.44. 

2. Lacerda G, Krummel T, Hirsch E. Neurologic presentations of renal diseases. Neurol Clin. 2010 Feb. 28(1):45-59 

3. Brouns R, De Deyn PP. Neurological complications in renal failure: a review. Clin Neurol Neurosurg. 2004 Dec. 107(1):1-16. 

4. Bansal VK, Bansal S. Nervous system disorders in dialysis patients. Handbook of Clinical Neurology. 2014. Vol 119 (3rd series):395-404.