A) Sodium
B) Potassium
C) Calcium
D) Magnesium
E) Phosphorus
Answer: C
The mechanism of action of Angiotensin II is known for more than four decades. Angiotensin II is part of the renin-aldosterone-angiotensin (RAAS) system. Angiotensin receptors i.e., AT1 & AT2 are G-coupled protein receptors and angiotensin-II as their ligand. Stimulation of AT1 & AT2 increases cytosolic calcium causing vasoconstriction. Moreover, it also increases aldosterone and vasopressin secretion.
#hemodynamics
References:
1. Catt KJ, Mendelsohn FA, Millan MA, Aguilera G. The role of angiotensin II receptors in vascular regulation. J Cardiovasc Pharmacol 1984; 6 Suppl 4:S575.
2. Fyhrquist F, Metsärinne K, Tikkanen I. Role of angiotensin II in blood pressure regulation and in the pathophysiology of cardiovascular disorders. J Hum Hypertens. 1995 Nov;9 Suppl 5:S19-24. PMID: 8583476.
3. Benigni A, Cassis P, Remuzzi G. Angiotensin II revisited: new roles in inflammation, immunology and aging. EMBO Mol Med. 2010;2(7):247-257. doi:10.1002/emmm.201000080
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