Thursday, December 2, 2021

Sodium in meningitis

 Q: Which is more common in acute bacterial meningitis? (select one) 

A) hypernatremia 

B) hyponatremia 

Answer: B

Concomitant abnormal laboratory findings are common in acute bacterial meningitis. It includes leucocytosis or leukopenia, thrombocytopenia, DIC, anion gap metabolic acidosis, and hyponatremia. 

Presence of leukopenia and/or thrombocytopenia is correlated with poor outcomes. On the other hand, the presence of hyponatremia has no bearing and doesn't require treatment.




1. Brouwer MC, van de Beek D, Heckenberg SG, et al. Hyponatraemia in adults with community-acquired bacterial meningitis. QJM 2007; 100:37. 

2. Kaplan SL. Clinical presentations, diagnosis, and prognostic factors of bacterial meningitis. Infect Dis Clin North Am 1999; 13:579. 

3. Kornelisse RF, Westerbeek CM, Spoor AB, et al. Pneumococcal meningitis in children: prognostic indicators and outcome. Clin Infect Dis 1995; 21:1390.

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