Friday, April 8, 2022

IV to PO morphine

 Q: What is an estimated IV to PO conversion ratio of Morphine?

Answer: 1:3

While converting intravenous (IV) to oral (PO) opioids two principles should be kept in mind 

  1. Conservative estimates should be used.
  2. The optimal dose should be found with judicious titration due to the fact that cross-tolerance equivalency is not established.
#pharmacology


Reference:

Calculating Conversations in Opioid Conversions 
url: https://www.fda.gov/media/150396/download (last accessed March 11, 2021)

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