Q: What is provocative Angiography?
Answer: Provocative angiography is rarely applied in lower gastrointestinal bleed (GIB), in case the site of bleeding cannot be identified by other conventional methods.
Provocative challenge is given with vasodilators, anticoagulants, and/or thrombolytics. The commonly used agents are urokinase, heparin, nicardipine in 3 cases, alprostadil, and isosorbide.
Although seem paradoxical but can be an effective way of identifying the area of bleed where there is a high risk of mortality.
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Reference:
Kariya S, Nakatani M, Ono Y, Maruyama T, Ueno Y, Yoshida A, Komemushi A, Tanigawa N. Provocative angiography for lower gastrointestinal bleeding. Jpn J Radiol. 2020 Mar;38(3):248-255. doi: 10.1007/s11604-019-00909-0. Epub 2019 Dec 13. PMID: 31834578.
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