Q: Crohn's Disease Activity Index (CDAI) in adults takes into account all of the following EXCEPT? (select one)
A) Gender
B) General wellbeing each day over 30 days
C) Iritis or uveitis
D) Anal fissure, fistula, or abscess
E) An abdominal mass
Answer; B
Crohn's Disease Activity Index (CDAI) in adults has been now widely used to determine the further line of management. Calculator (easily accessible on any search engine) is easy to put on data and gives points for various clinical signs and symptoms.
0 - 149 points: Asymptomatic remission
150 - 220 points: Mildly to moderately active Crohn's disease
221 - 450 points: Moderately to severely active Crohn's disease
451 - 1100 points: Severely active to fulminant disease
The answer is B as CDAI counts for general well-being in only the last 7 days.
It takes into account of
- Gender
- Weight
- Height
- Hematocrit
- Average number of liquid or soft stools per day over 7 days (14 points per stool)
- Using diphenoxylate or loperamide for diarrhea
- Average abdominal pain rating over 7 days
- General wellbeing each day over 7 days
- Arthritis or arthralgia
- Iritis or uveitis
- Erythema nodosum, pyoderma gangrenosum, or aphthous stomatitis
- Anal fissure, fistula, or abscess
- Other fistulae
- Temperature over 100°F (37.8°C) in the last week
- Finding an abdominal mass
#gastroenterology
References:
1. Best WR. Predicting the Crohn's disease activity index from the Harvey-Bradshaw Index. Inflamm Bowel Dis 2006; 12:304.
2. Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology 1976; 70:439.
3. Lichtenstein GR, Loftus EV, Isaacs KL, et al. ACG Clinical Guideline: Management of Crohn's Disease in Adults. Am J Gastroenterol 2018; 113:481.
4. Vermeire S, Schreiber S, Sandborn WJ, et al. Correlation between the Crohn's disease activity and Harvey-Bradshaw indices in assessing Crohn's disease severity. Clin Gastroenterol Hepatol 2010; 8:357.
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