Wednesday, November 23, 2022

Thiazide diuretics and urinary calcium excretion

Q: Thiazide diuretics _________ urinary calcium excretion? (select one)

A) increases
B) decreases


Answer: B

Thiazide diuretics decrease urinary calcium excretion. This effect makes it a good choice for patients who develop recurrent calcium nephrolithiasis. Also, it can be used in patients with any other cause of hypercalciuria. Although unlikely, patients already on thiazide diuretics should be watched for hypercalcemia, particularly those with underlying hyperparathyroidism.

#electrolytes
#pharmacology



Reference:

Grieff M, Bushinsky DA. Diuretics and disorders of calcium homeostasis. Semin Nephrol. 2011 Nov;31(6):535-41. doi: 10.1016/j.semnephrol.2011.09.008. PMID: 22099510.

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