Q: Sustained-release oral preparations of Magnesium are better absorbed.
A) True
B) False
Answer: A
The objective of this question is to negate the perception that in the ICU, there should always be an intravenous (IV) magnesium be used due to the high risk of diarrhea from oral prep. The sustained-release preparations are slowly and better absorbed, minimizing the risk of diarrhea and excretion via kidneys. Another reason for less diarrhea from sustained release as the total dose required is usually much lower to replete.
#electrolytes
References:
1. Weiss D, Brunk DK, Goodman DA. Scottsdale Magnesium Study: Absorption, Cellular Uptake, and Clinical Effectiveness of a Timed-Release Magnesium Supplement in a Standard Adult Clinical Population. J Am Coll Nutr. 2018 May-Jun;37(4):316-327. doi: 10.1080/07315724.2017.1398686. Epub 2018 Feb 9. PMID: 29425476.
2. Blancquaert L, Vervaet C, Derave W. Predicting and Testing Bioavailability of Magnesium Supplements. Nutrients. 2019 Jul 20;11(7):1663. doi: 10.3390/nu11071663. PMID: 31330811; PMCID: PMC6683096.
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