mumps meningitis

Q: Aseptic meningitis due to mumps is more common in males?

A) True

B) False

Answer: A

Aseptic meningitis is mumps' most common neurologic complication and was first reported more than six decades ago. For reasons not fully understood, it is three times more common in males. It can also cause orchitis and, in a few cases, sterility, particularly in non-vaccinated patients. 

Although aseptic meningitis is usually benign, it can occur before, during, or after mumps parotitis. To make diagnosis difficult, half of the cases related to mump parotitis, meningitis may occur without the symptoms of parotitis.

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References:

1. RUSSELL RR, DONALD JC. The neurological complications of mumps. Br Med J 1958; 2:27.

2. Johnstone JA, Ross CA, Dunn M. Meningitis and encephalitis associated with mumps infection. A 10-year survey. Arch Dis Child 1972; 47:647.

3. Rhie K, Park HK, Kim YS, Yeom JS, Park JS, Seo JH, Park ES, Lim JY, Park CH, Woo HO, Youn HS. Factors associated with mumps meningitis and the possible impact of vaccination. Korean J Pediatr. 2016 Jan;59(1):24-9. doi: 10.3345/kjp.2016.59.1.24. Epub 2016 Jan 22. PMID: 26893600; PMCID: PMC4753196.