Q; Name at least 7 non-septic conditions which can cause low SVR (systemic vascular resistance)?
Answer: Low SVR (vasoplegia) can be fatal. Also, it can take a lot of work to manage despite IVF and pressors. A few non-infectious causes of low SVR are below:
1. Hemorrhagic (or necrotizing) Pancreatitis
2. Cirrhosis
3. Adrenal insufficiency
4. Head Injury ( initially increased SVR followed by low SVR)
5. Bactrim (TMP-SMX) in AIDS patient
6. Within 6 hours of post cardiopulmonary bypass
7. Spinal cord Injury above T6 (inhibited vagal tone)
#hemodynamic
Further reading:
1. Lambden S, Creagh-Brown BC, Hunt J, Summers C, Forni LG. Definitions and pathophysiology of vasoplegic shock. Crit Care. 2018 Jul 6;22(1):174. doi: 10.1186/s13054-018-2102-1. PMID: 29980217; PMCID: PMC6035427.
2. Levy B, Fritz C, Tahon E, Jacquot A, Auchet T, Kimmoun A. Vasoplegia treatments: the past, the present, and the future. Crit Care. 2018 Feb 27;22(1):52. doi: 10.1186/s13054-018-1967-3. PMID: 29486781; PMCID: PMC6389278.
No comments:
Post a Comment