Monday, September 4, 2023

Gender ratio in fatal anaphylaxis

Q: Fatal anaphylaxis from contrast media is more common in? (select one)

A) Females
B) Males


Answer: B

For reasons not fully understood, males tend to have more fatal outcomes from contrast media. This is also true for insect stings.

When it comes to fatal food anaphylaxis, the sex ratio is approximately equal, but young boys are more prone to have fatal cow's milk reactions, and adolescent girls are affected more by peanut reactions.


#allergy
#immunology



References:

1. Pumphrey R. Anaphylaxis: can we tell who is at risk of a fatal reaction? Curr Opin Allergy Clin Immunol 2004; 4:285.

2. Bock SA, Muñoz-Furlong A, Sampson HA. Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol 2001; 107:191.

3. Pumphrey RS. Fatal anaphylaxis in the UK, 1992-2001. Novartis Found Symp 2004; 257:116.

4. Pouessel G, Claverie C, Labreuche J, et al. Fatal anaphylaxis in France: Analysis of national anaphylaxis data, 1979-2011. J Allergy Clin Immunol 2017; 140:610.

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