CPM after surgery

Q: Central Pontine Myelinolysis (CPM) may be a complication of which of the following post transplant surgery?

A) Heart

B) Liver 

C) Kidney

D) Pancreas

Answer: B

The other known causes of Central Pontine Myelinolysis (CPM) are

• Malnourishment
• rapid correction of hyponatremia 
• occasionally, after rapid correction of hypernatremia
• Wilson's disease
• Burn patients (with a prolonged period of serum hyperosmolality)
• withdrawal of chronic alcoholism
• post hematopoietic stem cell transplantation
• severe liver disease
• post liver transplantation
• severe burns
• malnutrition 
• hyperemesis gravidarum

#transplant

#surgical-critical-care

#neurology

References:

Singh N, Yu VL, Gayowski T. Central nervous system lesions in adult liver transplant recipients: clinical review with implications for management. Medicine (Baltimore). Mar 1994;73(2):110-8.

Adams RD, Victor M, Mancall EL. Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients. AMA Arch Neurol Psychiatry. Feb 1959;81(2):154-72. 

Kumar S, Fowler M, Gonzalez-Toledo E, Jaffe SL. Central pontine myelinolysis, an update. Neurol Res. Apr 2006;28(3):360-6.