Thrombotic Storm

Q: Give at least three causes of thrombotic storm?

Answer: Thrombotic storm is a dramatic clinical presentation with extensive systemic thrоmbοѕiѕ affecting multiple vascular beds. The most common causes are 

• Catastrophic Antiphospholipid Syndrome(CAΡЅ)
• Heparin-induced thrοmbοϲуtοрeոiа (HIT)
• Coronavirus disease 2019 (COVID-19)
• Trousseau syndrome (in certain cancers)

#Hematology

#rheumatology

#Covid

#oncology

References:

1. Kitchens CS, Erkan D, Brandão LR, et al. Thrombotic storm revisited: preliminary diagnostic criteria suggested by the thrombotic storm study group. Am J Med 2011; 124:290.

2. Ortel TL, Kitchens CS, Erkan D, Brandão LR, Hahn S, James AH, Kulkarni R, Manco-Johnson MJ, Pericak-Vance M, Vance J. Clinical causes and treatment of the thrombotic storm. Expert Rev Hematol. 2012 Dec;5(6):653-9. doi: 10.1586/ehm.12.56. PMID: 23216595.

3. Rodriguez JA, D'Silva K, Kohler M, Ghoshhajra B, Hedgire S. Catastrophic Thrombotic Storm. Clin Imaging. 2021 Jun;74:64-66. doi: 10.1016/j.clinimag.2020.12.025. Epub 2020 Dec 30. PMID: 33434868.