Cryoprecipitation

Q: Cryoprecipitation occurs below? - select one

A) 37°C

B) 35°C

C) 33°C

Answer: A

Precipitation of blood proteins at temperatures below 37°C is called cryoprecipitation.

This lower margin level is clinically significant, as surgical and non-surgical patients frequently arrive in the ICU with temperatures well below this temperature threshold. Cryoprecipitation occurs in two forms:

- Cryoglobulinemia, i.e., precipitation of blood proteins from serum and plasma. These patients may develop hyperviscosity or thrombosis. 

-Cryofibrinogenemia, i.e., precipitation of proteins from plasma. These patients may develop thrombosis.

#hematology

#hypothermia

Reference:

Ken Zafren, Daniel F Danzl, Michael Ganetsky - Nonfreezing cold water (trench foot) and warm water immersion injuries - https://www.uptodate.com/contents/nonfreezing-cold-water-trench-foot-and-warm-water-immersion-injuries (last accessed April 27, 2025) - © 2025 UpToDate, Inc. and/or its affiliates. All Rights Reserved.