Plasmapheresis during pregnancy

Q: A 32-year-old female, first-time, 26 weeks pregnant, with a known history of Myasthenia Gravis (MG), presented with severe myasthenia crisis requiring intubation. Plasmapheresis should not be performed during pregnancy.

 

A) True

B) False

Answer: B

Two major rescue therapies for myasthenic crisis are:

• Plasmapheresis 
• High-dose intravenous immune globulin

They are both safe in pregnancy.

#Ob-gyn

#neurology

References:

1. Varner M. Myasthenia gravis and pregnancy. Clin Obstet Gynecol 2013; 56:372.

2. Sanders DB, Wolfe GI, Benatar M, et al. International consensus guidance for management of myasthenia gravis: Executive summary. Neurology 2016; 87:419.

3. Watson WJ, Katz VL, Bowes WA Jr. Plasmapheresis during pregnancy. Obstet Gynecol 1990; 76:451.