Q: Why Albumin is used in Liver dialysis?
Answer:
Liver dialysis is similar to hemodialysis and based on the same principles. Hemodialysis removes only water soluble toxins and does not remove toxins bound to albumin. Therefore, the removal of lipophilic, albumin-bound substances such as bilirubin, bile acids, metabolites of aromatic amino acids, medium-chain fatty acids and cytokines require albumin in liver dialysis. Liver dialysis is only a short term bridge to transplantation or liver recovery and, unlike renal dialysis cannot go for an extended period. Single Pass Albumin Dialysis (SPAD) is a simple method of albumin dialysis using standard renal replacement therapy machines without an additional perfusion pump system.
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