Q: Which part of the bodies are more prone to be "Red" in "Red Man
Syndrome" secondary to IV Vancomycin?
Answer: Face, Neck and Upper Torso
"Red man syndrome" is a potential side effect that may occur with
vancomycin administration. It is not a true allergic reaction and
is probably related to the release of histamine.
It can be avoided with slowing (over 2 hours) and diluting the
infusion and with previous history or concern for any risk, pre-treatment with a
histamine-1 antagonist prior to any further dose may help.
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