Q:What is the risk of adding bicarbonate in IVF during treatment of Rhabdomyolysis?

Answer: The addition of bicarbonate to the IVF to make the urine more alkaline to prevent cast formation in the kidneys is no more recommended. Data fail to show any benefit above saline alone, and actually it can worsen hypocalcemia by enhancing calcium and phosphate deposition in the tissues.

References:

1. Huerta-Alardín AL; Varon J; Marik PE (2005). "Bench-to-bedside review: rhabdomyolysis – an overview for clinicians". Critical Care 9 (2): 158–69.

2.  Vanholder R; Sever MS; Erek E; Lameire N (1 August 2000). "Rhabdomyolysis". Journal of the American Society of Nephrology 11 (8): 1553–61.