Q: Peliosis hepatis in chronic kidney disease patients get treated by kidney transplantation?
Peliosis hepatis, first described about 70 years ago, is one dreaded disease which has many etiologies but unfortunately no specific treatment. Moreover, it goes undiagnosed without any symptom for an extended period. Although mostly limited to the liver, it may occur in other organs such as spleen or lungs. By definition, it a proliferation of the sinusoidal hepatic capillaries that results in cystic blood-filled cavities throughout the liver. It may occur due to drugs (steroids are the most common), underlying immune disorders or infections particularly with tuberculosis.
For reasons not clearly understood, in renal patients peliosis hepatis either gets acquired or gets worse after transplant. Probable etiologies are immunosuppressant drugs or development of opportunistic infections after transplantation.
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