Wednesday, June 19, 2019

Phenytoin in theo seizure

Q: Phenytoin may intensify the seizures caused by theophylline? (select one)

A) True
B) False


Answer: A

Phenytoin as well as its pro-drug fosphenytoin may make seizures caused by cocaine and theophylline worse!  Intravenous 
Benzodiazepines is the preferred drug of treatment.
 


#neurology

#pharmacology


References:


1. Wills B, Erickson T. Chemically induced seizures. Clin Lab Med 2006; 26:185. 


2. Paloucek FP, Rodvold KA. Evaluation of theophylline overdoses and toxicities. Ann Emerg Med 1988; 17:135.

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